MolNFT v1 · #51477 · protein

Structure of the murray valley encephalitis virus RNA helicase to 1. 9A resolution

2V8O · Flavivirin protease NS3: “Structure of the murray valley encephalitis virus RNA helicase to 1. 9A resolution”. X-ray diffraction, 4 pockets (best druggability 0.83). MolNFT v1 #51477 on GenesisL1: 3D structure, binding sites and…

PDB: 2V8O
Type: protein
Length: 429 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flavivirin protease NS3
EC: 3.4.21.91
UniProt: P05769
Pockets: 4 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flavivirin protease NS3 (EC 3.4.21.91)	protein	429	34% helix, 16% strand	P05769

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1143	0.83	0.84	95	empty
2	321	0.67	0.82	44	empty
3	51	0.53	0.88	11	empty
4	62	0.32	0.76	20	empty

Compared structures

2V8O · Structure of the Murray Valley encephalitis virus RNA helicase to 1. 9A resolution · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05769
Elsewhere: RCSB PDB 2V8O · PDBe 2V8O · UniProt P05769

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