MolNFT v1 · #51320 · protein
Structure of the ligand-binding core of the ionotropic glutamate receptor-like GLURDELTA2 in complex with D-serine
2V3U · Glutamate receptor delta-2 subunit: “Structure of the ligand-binding core of the ionotropic glutamate receptor-like GLURDELTA2 in complex with…”. X-ray diffraction, 4 ligands (DSN, NA, SCN), 2 pockets (best druggability 0.43).…
- PDB
- 2V3U
- Type
- protein
- Length
- 253 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamate receptor delta-2 subunit
- UniProt
- Q63226
- Ligands
- DSN, NA, SCN, CL
- Pockets
- 2 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate receptor delta-2 subunit | protein | 253 | 36% helix, 22% strand | Q63226 |
Ligands and binding sites
- DSN · D-serine · ligand · chains A
- NA · Sodium ion · metal · chains A
- SCN · Thiocyanate ion · ion · 2 copies · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.43 | 0.79 | 20 | CL |
| 2 | 73 | 0.39 | 0.78 | 17 | SCN |
Compared structures
- 2V3U · Structure of the ligand-binding core of the ionotropic glutamate receptor-like GluRdelta2… · the same entry in another collection · chain A against A, TM-score 1.00
- Q63226 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, delta-2 (Q63226) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q63226
- Elsewhere: RCSB PDB 2V3U · PDBe 2V3U · UniProt Q63226
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