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Ligand · DSN

DSN · D-serine

DSN, D-serine (C3 H7 N O3, 105.1 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DSN
Formula
C3 H7 N O3
Class
ligand
Structures
8
PDB entries
8

Binding sites

DSN in 8 structures; the first of them:

  • 6QW7 · Crystal structure of L2 complexed with relebactam (16 hour soak) · DSN A301 · binds CYS69, SER70, HIS105, SER130, ASN132, ASN170, THR235, GLY236 and 1 more
  • 6TGH · SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as… · DSN C502 · binds GLU57, TYR65, SER35, HIS126, SER176, HIS204, LYS230, ARG363
  • 6YRW · SHMT from Streptococcus thermophilus Tyr55Ser variant as internal aldimine and as… · DSN A502 · binds SER35, HIS126, SER176, HIS204, LYS230, ARG363, GLU57, TYR65
  • 6YX7 · The high resolution structure of allophycocyanin from cyanobacterium Nostoc sp. WR13, the… · DSN JJJ202 · binds ARG107, VAL108, ASN110, GLY111, LEU112, THR115
  • 7A8Y · X-ray crystal structure of Aspartate alpha-decarboxylase in complex with D-Serine · DSN BBB201 · binds TYR22, SER25, THR57, TYR58, ASN72, GLY73, ALA74
  • 8BN2 · Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in… · DSN A907 · binds TYR492, ALA519, ILE520, THR521, ARG526, TYR539, ALA686, VAL687 and 3 more
  • 8SSY · Room-temperature X-ray structure of Thermus thermophilus serine hydroxymethyltransferase… · DSN A501 · binds SER31, SER172, HIS200, LLP226, ARG358, TYR51, GLU53, TYR61
  • 8WNY · Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state · DSN B1001 · binds ASN52, ILE53, ILE54, GLY55, SER56, GLY57, SER134, ILE138 and 5 more

Residues it binds most

SER 12, TYR 12, HIS 9, ARG 10, GLY 7, ASN 7, GLU 7, LYS 7, THR 7, ALA 4 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • PLP · Pyridoxal-5'-phosphate
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • ALA · Alanine
  • CYC · Phycocyanobilin
  • EVM · L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene]
  • GLU · Glutamic acid
  • GLY · Glycine
  • LYS · Lysine
  • MK7 · (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy) amino]piperidine-2-carboxamide
  • SER · Serine
  • CA · Calcium ion

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