MolNFT v1 · #51010 · protein
The 2.4 ångström resolution structure of the D346G mutant of the sapporo virus rdrp polymerase
2UUT · RNA-directed RNA polymerase: “The 2.4 ångström resolution structure of the D346G mutant of the sapporo virus rdrp polymerase”. X-ray diffraction, 4 pockets (best druggability 0.59). MolNFT v1 #51010 on GenesisL1: 3D structure…
- PDB
- 2UUT
- Type
- protein
- Length
- 492 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-directed RNA polymerase
- EC
- 2.7.7.48
- UniProt
- Q69014
- Pockets
- 4 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-directed RNA polymerase (EC 2.7.7.48) | protein | 492 | 43% helix, 17% strand | Q69014 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 393 | 0.59 | 0.76 | 32 | empty |
| 2 | 335 | 0.54 | 0.74 | 42 | empty |
| 3 | 131 | 0.36 | 0.72 | 20 | empty |
| 4 | 62 | 0.29 | 0.74 | 20 | empty |
Compared structures
- 2UUT · The 2.4 angstrom resolution structure of the D346G mutant of the Sapporo Virus RdRp… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q69014
- Elsewhere: RCSB PDB 2UUT · PDBe 2UUT · UniProt Q69014
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.