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The 2.4 ångström resolution structure of the D346G mutant of the sapporo virus rdrp polymerase
Analyse The 2.4 ångström resolution structure of the D346G mutant of the sapporo virus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2UUT
- Type
- protein
- Length
- 492 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-directed RNA polymerase
- EC
- 2.7.7.48
- UniProt
- Q69014
- Pockets
- 4 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-directed RNA polymerase (EC 2.7.7.48) | protein | 492 | 43% helix, 17% strand | Q69014 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 393 | 0.59 | 0.76 | 32 | empty |
| 2 | 335 | 0.54 | 0.74 | 42 | empty |
| 3 | 131 | 0.36 | 0.72 | 20 | empty |
| 4 | 62 | 0.29 | 0.74 | 20 | empty |
Compared structures
- 2UUT · The 2.4 angstrom resolution structure of the D346G mutant of the Sapporo Virus RdRp… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q69014
- Elsewhere: RCSB PDB 2UUT · PDBe 2UUT · UniProt Q69014
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