MolNFT v1 · #50975 · protein

Solution structure of the second RNA-binding domain of HU2AF65

2U2F · Protein (splicing factor U2AF 65 kd subunit): “Solution structure of the second RNA-binding domain of HU2AF65”. Solution nmr, 1 pocket (best druggability 0.40). MolNFT v1 #50975 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 2U2F
Type: protein
Length: 85 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (splicing factor U2AF 65 kd subunit)
UniProt: P26368
Pockets: 1 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 18% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (splicing factor U2AF 65 kd subunit)	protein	85	18% helix, 25% strand	P26368

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	89	0.40	0.76	15	empty

Compared structures

2U2F · Solution structure of the second RNA-binding domain of HU2AF65 · the same entry in another collection · chain A against A, TM-score 1.00
P26368 · AlphaFold monomer V2.0 prediction for splicing factor U2AF 65 kda subunit (P26368) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26368
Elsewhere: RCSB PDB 2U2F · PDBe 2U2F · UniProt P26368

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