MolNFT v1 · #50945 · protein

Four calcium tnc

2TN4 · Troponin C: “Four calcium tnc”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.37). MolNFT v1 #50945 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2TN4
Type: protein
Length: 155 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Troponin C
UniProt: P02586
Ligands: CA
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Troponin C	protein	155	66% helix, 4% strand	P02586

Ligands and binding sites

CA · Calcium ion · metal · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.37	0.77	14	empty

Compared structures

2TN4 · Four calcium tnc · the same entry in another collection · chain A against A, TM-score 1.00
P02586 · AlphaFold monomer V2.0 prediction for troponin C, skeletal muscle (P02586) · a predicted model of the same protein · chain A against A, TM-score 0.64

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02586
Elsewhere: RCSB PDB 2TN4 · PDBe 2TN4 · UniProt P02586

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