MolNFT v1 · #50800 · protein + RNA
Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein
2RU7 · RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'): “Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein”. Solution nmr. MolNFT v1 #50800 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2RU7
- Type
- protein + RNA
- Length
- 48 residues
- Chains
- 4
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'); P16 peptide from major prion protein
- UniProt
- P10279
Structure
solution nmr · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | rna | 12 | — | — |
| C, D | P16 peptide from major prion protein | protein | 12 | 0% helix, 0% strand | P10279 |
Interfaces
3 interfaces between chains.
- A–B · 702 Ų buried · 30 hydrogen bonds · nucleic-nucleic
- A–C · 490 Ų buried · 13 hydrogen bonds · protein-nucleic
- B–D · 420 Ų buried · 15 hydrogen bonds · protein-nucleic
Compared structures
- 2RU7 · Refined structure of RNA aptamer in complex with the partial binding peptide of prion… · the same entry in another collection · chain D against D, TM-score 1.00
- P10279 · AlphaFold monomer V2.0 prediction for major prion protein (P10279) · a predicted model of the same protein · chain C against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10279
- Elsewhere: RCSB PDB 2RU7 · PDBe 2RU7 · UniProt P10279
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