MolNFT v1 · #50749 · protein + RNA
RNA aptamer against prion protein in complex with the partial binding peptide
2RSK · RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'): “RNA aptamer against prion protein in complex with the partial binding peptide”. Solution nmr. MolNFT v1 #50749 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2RSK
- Type
- protein + RNA
- Length
- 48 residues
- Chains
- 4
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'); Partial binding peptide of major…
- UniProt
- P10279
Structure
solution nmr · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | rna | 12 | — | — |
| C, D | Partial binding peptide of major prion protein | protein | 12 | 0% helix, 0% strand | P10279 |
Interfaces
3 interfaces between chains.
- A–B · 679 Ų buried · 102 hydrogen bonds · nucleic-nucleic
- A–C · 441 Ų buried · 24 hydrogen bonds · protein-nucleic
- B–D · 436 Ų buried · 25 hydrogen bonds · protein-nucleic
Compared structures
- 2RSK · RNA aptamer against prion protein in complex with the partial binding peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P10279 · AlphaFold monomer V2.0 prediction for major prion protein (P10279) · a predicted model of the same protein · chain C against A, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10279
- Elsewhere: RCSB PDB 2RSK · PDBe 2RSK · UniProt P10279
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