Research workbench
RNA aptamer against prion protein in complex with the partial binding peptide
Analyse RNA aptamer against prion protein in complex with the partial binding peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2RSK
- Type
- protein + RNA
- Length
- 48 residues
- Chains
- 4
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'); Partial binding peptide of major…
- UniProt
- P10279
Structure
solution nmr · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | rna | 12 | — | — |
| C, D | Partial binding peptide of major prion protein | protein | 12 | 0% helix, 0% strand | P10279 |
Interfaces
3 interfaces between chains.
- A–B · 679 Ų buried · 102 hydrogen bonds · nucleic-nucleic
- A–C · 441 Ų buried · 24 hydrogen bonds · protein-nucleic
- B–D · 436 Ų buried · 25 hydrogen bonds · protein-nucleic
Compared structures
- 2RSK · RNA aptamer against prion protein in complex with the partial binding peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P10279 · AlphaFold monomer V2.0 prediction for major prion protein (P10279) · a predicted model of the same protein · chain C against A, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10279
- Elsewhere: RCSB PDB 2RSK · PDBe 2RSK · UniProt P10279
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