MolNFT v1 · #50562 · protein

Solution structure of the lsm domain of dm EDC3 (enhancer of decapping 3)

2RM4 · CG6311-pb: “Solution structure of the lsm domain of dm EDC3 (enhancer of decapping 3)”. Solution nmr, 1 pocket (best druggability 0.43). MolNFT v1 #50562 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2RM4
Type: protein
Length: 103 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CG6311-pb
UniProt: Q9VVI2
Pockets: 1 · best druggability 0.43

Structure

solution nmr · 1 distinct chain · 3% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CG6311-pb	protein	103	3% helix, 38% strand	Q9VVI2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.43	0.80	21	empty

Compared structures

2RM4 · Solution Structure of the LSM Domain of Dm EDC3 (Enhancer of DECAPPING 3) · the same entry in another collection · chain A against A, TM-score 1.00
Q9VVI2 · AlphaFold monomer V2.0 prediction for enhancer of mRNA-decapping protein 3 (Q9VVI2) · a predicted model of the same protein · chain A against A, TM-score 0.66

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9VVI2
Elsewhere: RCSB PDB 2RM4 · PDBe 2RM4 · UniProt Q9VVI2

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