MolNFT v1 · #50522 · protein

Crystal structure of the VPS4P-dimer

2RKO · Vacuolar protein sorting-associated protein 4: “Crystal structure of the VPS4P-dimer”. X-ray diffraction, 1 pocket (best druggability 0.63). MolNFT v1 #50522 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2RKO
Type: protein
Length: 280 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vacuolar protein sorting-associated protein 4
UniProt: P52917
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vacuolar protein sorting-associated protein 4	protein	280	46% helix, 13% strand	P52917

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	218	0.63	0.82	29	empty

Compared structures

2RKO · Crystal Structure of the Vps4p-dimer · the same entry in another collection · chain A against A, TM-score 1.00
P52917 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 4… · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52917
Elsewhere: RCSB PDB 2RKO · PDBe 2RKO · UniProt P52917

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