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MolNFT v1 · #50467 · protein

Crystal structure of the sugar recognizing scf ubiquitin ligase at 1.7 resolution

2RJ2 · F-box only protein 2: “Crystal structure of the sugar recognizing scf ubiquitin ligase at 1.7 resolution”. X-ray diffraction, 2 ligands (NI, CL), 1 pocket (best druggability 0.48). MolNFT v1 #50467 on GenesisL1: 3D structure…

PDB
2RJ2
Type
protein
Length
185 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
F-box only protein 2
EC
6.3.2.19
UniProt
Q80UW2
Ligands
NI, CL
Pockets
1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 42% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AF-box only protein 2 (EC 6.3.2.19)protein1858% helix, 42% strandQ80UW2

Ligands and binding sites

  • NI · Nickel (II) ion · metal · chains A
  • CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1740.480.8319empty

Compared structures

  • 2RJ2 · Crystal Structure of the Sugar Recognizing SCF Ubiquitin Ligase at 1.7 Resolution · the same entry in another collection · chain A against A, TM-score 1.00
  • Q80UW2 · AlphaFold monomer V2.0 prediction for F-box only protein 2 (Q80UW2) · a predicted model of the same protein · chain A against A, TM-score 0.97

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