MolNFT v1 · #50322 · protein
Crystal structure of the PDZ domain of human dishevelled 2 (homologous to drosophila dsh)
2REY · Segment polarity protein dishevelled homolog dvl-2: “Crystal structure of the PDZ domain of human dishevelled 2 (homologous to drosophila dsh)”. X-ray diffraction, 1 pocket (best druggability 0.39). MolNFT v1 #50322 on GenesisL1: 3D…
- PDB
- 2REY
- Type
- protein
- Length
- 91 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Segment polarity protein dishevelled homolog dvl-2
- UniProt
- O14641
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 18% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Segment polarity protein dishevelled homolog dvl-2 | protein | 91 | 18% helix, 32% strand | O14641 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.39 | 0.79 | 11 | empty |
Compared structures
- 2REY · Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh) · the same entry in another collection · chain A against A, TM-score 1.00
- O14641 · AlphaFold monomer V2.0 prediction for segment polarity protein dishevelled homolog dvl-2… · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14641
- Elsewhere: RCSB PDB 2REY · PDBe 2REY · UniProt O14641
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