MolNFT v1 · #50251 · protein

Crystal structure of human holo cellular retinol-binding protein II (crbp-II)

2RCT · Retinol-binding protein II, cellular: “Crystal structure of human holo cellular retinol-binding protein II (crbp-II)”. X-ray diffraction, 2 ligands (RTL, SO4), 1 pocket (best druggability 0.83). MolNFT v1 #50251 on GenesisL1: 3D…

PDB: 2RCT
Type: protein
Length: 141 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Retinol-binding protein II, cellular
UniProt: P50120
Ligands: RTL, SO4
Pockets: 1 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Retinol-binding protein II, cellular	protein	141	10% helix, 53% strand	P50120

Ligands and binding sites

RTL · Retinol · ligand · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A
TLA · L(+)-tartaric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	242	0.83	0.95	32	RTL

Compared structures

2RCT · Crystal structure of human holo cellular retinol-binding protein II (CRBP-II) · the same entry in another collection · chain A against A, TM-score 1.00
P50120 · AlphaFold monomer V2.0 prediction for retinol-binding protein 2 (P50120) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50120
Elsewhere: RCSB PDB 2RCT · PDBe 2RCT · UniProt P50120

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