MolNFT v1 · #49969 · protein
Crystal structure of a C1190S mutant of the 6TH PDZ domain of human membrane associated guanylate kinase
2R4H · Membrane-associated guanylate kinase, ww and PDZ domain…: “Crystal structure of a C1190S mutant of the 6TH PDZ domain of human membrane associated guanylate kinase”. X-ray diffraction. MolNFT v1 #49969 on GenesisL1: 3D structure…
- PDB
- 2R4H
- Type
- protein
- Length
- 282 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Membrane-associated guanylate kinase, ww and PDZ domain- containing protein 1
- UniProt
- Q96QZ7
Structure
x-ray diffraction · 3 distinct chains · 21% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Membrane-associated guanylate kinase, ww and PDZ domain- containing protein 1 | protein | 92 | 17% helix, 40% strand | Q96QZ7 |
| B | Membrane-associated guanylate kinase, ww and PDZ domain- containing protein 1 | protein | 89 | 19% helix, 42% strand | Q96QZ7 |
| C | Membrane-associated guanylate kinase, ww and PDZ domain- containing protein 1 | protein | 101 | 27% helix, 37% strand | Q96QZ7 |
Interfaces
2 interfaces between chains.
- A–C · 729 Ų buried · 19 hydrogen bonds · protein-protein
- A–B · 438 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 2R4H · Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated… · the same entry in another collection · chain A against A, TM-score 1.00
- Q96QZ7 · AlphaFold monomer V2.0 prediction for membrane-associated guanylate kinase, ww and PDZ… · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96QZ7
- Elsewhere: RCSB PDB 2R4H · PDBe 2R4H · UniProt Q96QZ7
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