MolNFT v1 · #49841 · protein

Crystal structure of human saposin D variant sapd K9E

2R0R · Proactivator polypeptide: “Crystal structure of human saposin D variant sapd K9E”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #49841 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2R0R
Type: protein
Length: 155 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proactivator polypeptide
UniProt: P07602
Ligands: SO4

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proactivator polypeptide	protein	77	74% helix, 0% strand	P07602
B	Proactivator polypeptide	protein	78	73% helix, 0% strand	P07602

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 472 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

2R0R · Crystal Structure of Human Saposin D variant SapD K9E · the same entry in another collection · chain A against A, TM-score 1.00
P07602 · AlphaFold monomer V2.0 prediction for prosaposin (P07602) · a predicted model of the same protein · chain B against A, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07602
Elsewhere: RCSB PDB 2R0R · PDBe 2R0R · UniProt P07602

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