MolNFT v1 · #48877 · protein

Sall double mutant Y70T/G131S with clda and L-met

2Q6L · Hypothetical protein: “Sall double mutant Y70T/G131S with clda and L-met”. X-ray diffraction, 2 ligands (5CD, MET), 2 pockets (best druggability 0.52). MolNFT v1 #48877 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2Q6L
Type: protein
Length: 257 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein
UniProt: A4X3Q0
Ligands: 5CD, MET
Pockets: 2 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein	protein	257	24% helix, 30% strand	A4X3Q0

Ligands and binding sites

5CD · 5'-chloro-5'-deoxyadenosine · ligand · chains A
MET · Methionine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	147	0.52	0.79	15	empty
2	72	0.47	0.82	15	empty

Compared structures

2Q6L · SalL double mutant Y70T/G131S with CLDA and L-MET · the same entry in another collection · chain A against A, TM-score 1.00
A4X3Q0 · AlphaFold monomer V2.0 prediction for adenosyl-chloride synthase (A4X3Q0) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4X3Q0
Elsewhere: RCSB PDB 2Q6L · PDBe 2Q6L · UniProt A4X3Q0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.