MolNFT v1 · #48410 · protein
Crystal structures of the luciferase and green fluorescent protein from renilla reniformis
2PSF · Renilla-luciferin 2-monooxygenase: “Crystal structures of the luciferase and green fluorescent protein from renilla reniformis”. X-ray diffraction, 5 pockets (best druggability 0.76). MolNFT v1 #48410 on GenesisL1: 3D structure…
- PDB
- 2PSF
- Type
- protein
- Length
- 608 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Renilla-luciferin 2-monooxygenase
- EC
- 1.13.12.5
- UniProt
- P27652
- Pockets
- 5 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Renilla-luciferin 2-monooxygenase (EC 1.13.12.5) | protein | 307 | 43% helix, 18% strand | P27652 |
| B | Renilla-luciferin 2-monooxygenase (EC 1.13.12.5) | protein | 301 | 42% helix, 19% strand | P27652 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 286 | 0.76 | 0.88 | 40 | empty |
| 2 | 341 | 0.75 | 0.86 | 38 | empty |
| 3 | 441 | 0.62 | 0.76 | 40 | empty |
| 4 | 78 | 0.38 | 0.79 | 15 | empty |
| 5 | 51 | 0.25 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 596 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 2PSF · Crystal Structures of the Luciferase and Green Fluorescent Protein from Renilla Reniformis · the same entry in another collection · chain A against A, TM-score 1.00
- P27652 · AlphaFold monomer V2.0 prediction for coelenterazine H 2-monooxygenase (P27652) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27652
- Elsewhere: RCSB PDB 2PSF · PDBe 2PSF · UniProt P27652
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