MolNFT v1 · #48272 · protein

X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase

2PO4: “X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase”. X-ray diffraction, 14 pockets (best druggability 0.85). MolNFT v1 #48272 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2PO4
Type: protein
Length: 1,094 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Virion RNA polymerase
EC: 2.7.7.6
UniProt: Q859P9
Pockets: 14 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 57% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Virion RNA polymerase (EC 2.7.7.6)	protein	1094	57% helix, 11% strand	Q859P9

Pockets

14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	776	0.85	0.89	87	empty
2	277	0.79	0.91	44	empty
3	614	0.69	0.78	53	empty
4	91	0.55	0.86	17	empty
5	119	0.48	0.79	20	empty

Compared structures

2PO4 · X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q859P9
Elsewhere: RCSB PDB 2PO4 · PDBe 2PO4 · UniProt Q859P9

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