MolNFT v1 · #47857 · protein
Crystal structure of the sra domain of the human UHRF1 protein
2PB7 · E3 ubiquitin-protein ligase UHRF1: “Crystal structure of the sra domain of the human UHRF1 protein”. X-ray diffraction, 1 pocket (best druggability 0.53). MolNFT v1 #47857 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2PB7
- Type
- protein
- Length
- 197 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase UHRF1
- EC
- 6.3.2.-
- UniProt
- Q96T88
- Pockets
- 1 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) | protein | 197 | 16% helix, 27% strand | Q96T88 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.53 | 0.82 | 28 | empty |
Compared structures
- 2PB7 · Crystal Structure of the SRA domain of the human UHRF1 protein · the same entry in another collection · chain A against A, TM-score 1.00
- Q96T88 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase UHRF1 (Q96T88) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96T88
- Elsewhere: RCSB PDB 2PB7 · PDBe 2PB7 · UniProt Q96T88
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