MolNFT v1 · #47765 · RNA

Solution structure of the 3' pseudouridyation pocket of U65 snorna with bound substrate

2P89 · U65 H/ACA snorna: “Solution structure of the 3' pseudouridyation pocket of U65 snorna with bound substrate”. Solution nmr, 1 pocket (best druggability 0.47). MolNFT v1 #47765 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2P89
Type: RNA
Length: 48 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U65 H/ACA snorna; 28S rRNA
Pockets: 1 · best druggability 0.47

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	U65 H/ACA snorna	rna	34	—	—
B	28S rRNA	rna	14	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	263	0.47	0.73	15	empty

Interfaces

1 interface between chains.

A–B · 874 Å² buried · 48 hydrogen bonds · nucleic-nucleic

Compared structures

2P89 · Solution structure of the 3' pseudouridyation pocket of U65 snoRNA with bound substrate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2P89 · PDBe 2P89

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