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Solution structure of the 3' pseudouridyation pocket of U65 snorna with bound substrate

Analyse Solution structure of the 3' pseudouridyation pocket of U65 snorna with bound… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2P89
Type: RNA
Length: 48 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U65 H/ACA snorna; 28S rRNA
Pockets: 1 · best druggability 0.47

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	U65 H/ACA snorna	rna	34	—	—
B	28S rRNA	rna	14	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	263	0.47	0.73	15	empty

Interfaces

1 interface between chains.

A–B · 874 Å² buried · 48 hydrogen bonds · nucleic-nucleic

Compared structures

2P89 · Solution structure of the 3' pseudouridyation pocket of U65 snoRNA with bound substrate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2P89 · PDBe 2P89

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