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MolNFT v1 · #47629 · protein

Complex of a camelid single-domain vhh antibody fragment with RNase a at 1.4A resolution: native MONO_1 crystal form

2P49 · Ribonuclease pancreatic: “Complex of a camelid single-domain vhh antibody fragment with RNase a at 1.4A resolution: native MONO_1…”. X-ray diffraction, 1 ligand (PO4). MolNFT v1 #47629 on GenesisL1: 3D structure, binding sites and…

PDB
2P49
Type
protein
Length
242 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ribonuclease pancreatic; Antibody cab-RN05
EC
3.1.27.5
UniProt
P61823
Ligands
PO4

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 43% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibonuclease pancreatic (EC 3.1.27.5)protein11922% helix, 37% strandP61823
BAntibody cab-RN05protein1237% helix, 48% strand—

Ligands and binding sites

  • PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 642 Ų buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

  • 2P49 · Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution… · the same entry in another collection · chain A against A, TM-score 1.00

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