MolNFT v1 · #47629 · protein
Complex of a camelid single-domain vhh antibody fragment with RNase a at 1.4A resolution: native MONO_1 crystal form
2P49 · Ribonuclease pancreatic: “Complex of a camelid single-domain vhh antibody fragment with RNase a at 1.4A resolution: native MONO_1…”. X-ray diffraction, 1 ligand (PO4). MolNFT v1 #47629 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2P49
- Type
- protein
- Length
- 242 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonuclease pancreatic; Antibody cab-RN05
- EC
- 3.1.27.5
- UniProt
- P61823
- Ligands
- PO4
Structure
x-ray diffraction · 2 distinct chains · 14% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonuclease pancreatic (EC 3.1.27.5) | protein | 119 | 22% helix, 37% strand | P61823 |
| B | Antibody cab-RN05 | protein | 123 | 7% helix, 48% strand | — |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 642 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 2P49 · Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61823
- Elsewhere: RCSB PDB 2P49 · PDBe 2P49 · UniProt P61823
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