MolNFT v1 · #47627 · protein
Complex of a camelid single-domain vhh antibody fragment with RNase a at 2.5A resolution: SE5B-tri crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
2P47 · Ribonuclease pancreatic: “Complex of a camelid single-domain vhh antibody fragment with RNase a at 2.5A resolution: SE5B-tri crystal…”. X-ray diffraction. MolNFT v1 #47627 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2P47
- Type
- protein
- Length
- 244 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonuclease pancreatic; Antibody cab-RN05
- EC
- 3.1.27.5
- UniProt
- P61823
Structure
x-ray diffraction · 2 distinct chains · 13% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonuclease pancreatic (EC 3.1.27.5) | protein | 123 | 21% helix, 34% strand | P61823 |
| B | Antibody cab-RN05 | protein | 121 | 5% helix, 48% strand | — |
Interfaces
1 interface between chains.
- A–B · 611 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified, 4 disulfide (engineered, disulfide).
Compared structures
- 2P47 · Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61823
- Elsewhere: RCSB PDB 2P47 · PDBe 2P47 · UniProt P61823
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