MolNFT v1 · #47179 · protein
The structure of the response regulator REGX3 from mycobacterium tuberculosis
2OQR · Sensory transduction protein REGX3: “The structure of the response regulator REGX3 from mycobacterium tuberculosis”. X-ray diffraction, 1 ligand (LA), 1 pocket (best druggability 0.35). MolNFT v1 #47179 on GenesisL1: 3D structure…
- PDB
- 2OQR
- Type
- protein
- Length
- 226 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sensory transduction protein REGX3
- UniProt
- Q11156
- Ligands
- LA
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sensory transduction protein REGX3 | protein | 226 | 42% helix, 19% strand | Q11156 |
Ligands and binding sites
- LA · Lanthanum (III) ion · metal · 5 copies · chains A
- ACT · Acetate ion · additive · 2 copies · chains A
- BME · Beta-mercaptoethanol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.35 | 0.76 | 17 | empty |
Compared structures
- 2OQR · The structure of the response regulator RegX3 from Mycobacterium tuberculosis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q11156
- Elsewhere: RCSB PDB 2OQR · PDBe 2OQR · UniProt Q11156
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