MolNFT v1 · #4689 · protein
Latent form of plasminogen activator inhibitor-1 (pai-1)
1DVN: “Latent form of plasminogen activator inhibitor-1 (pai-1)”. X-ray diffraction, 2 pockets (best druggability 0.47). MolNFT v1 #4689 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1DVN
- Type
- protein
- Length
- 379 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plasminogen activator inhibitor-1
- UniProt
- P05121
- Pockets
- 2 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plasminogen activator inhibitor-1 | protein | 379 | 29% helix, 34% strand | P05121 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 144 | 0.47 | 0.77 | 19 | empty |
| 2 | 110 | 0.44 | 0.77 | 23 | empty |
Compared structures
- 1DVN · Latent form of plasminogen activator inhibitor-1 (pai-1) · the same entry in another collection · chain A against A, TM-score 1.00
- P05121 · AlphaFold monomer V2.0 prediction for plasminogen activator inhibitor 1 (P05121) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05121
- Elsewhere: RCSB PDB 1DVN · PDBe 1DVN · UniProt P05121
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