MolNFT v1 · #46845 · protein
Molecular and structural basis of PLK1 substrate recognition: implications in centrosomal localization
2OGQ · SERINE/THREONINE-protein kinase PLK1: “Molecular and structural basis of PLK1 substrate recognition: implications in centrosomal localization”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #46845 on GenesisL1: 3D…
- PDB
- 2OGQ
- Type
- protein
- Length
- 211 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase PLK1
- EC
- 2.7.11.21
- UniProt
- P53350
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase PLK1 (EC 2.7.11.21) | protein | 211 | 32% helix, 31% strand | P53350 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.40 | 0.75 | 21 | empty |
| 2 | 53 | 0.36 | 0.79 | 14 | empty |
Compared structures
- 2OGQ · Molecular and structural basis of Plk1 substrate recognition: Implications in centrosomal… · the same entry in another collection · chain A against A, TM-score 1.00
- P53350 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase PLK1 (P53350) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53350
- Elsewhere: RCSB PDB 2OGQ · PDBe 2OGQ · UniProt P53350
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