MolNFT v1 · #46481 · protein
Crystal structure of the full length ferric pyoverdine outer membrane receptor fpva of pseudomonas aeruginosa in its apo form
2O5P · Ferripyoverdine receptor: “Crystal structure of the full length ferric pyoverdine outer membrane receptor fpva of pseudomonas aeruginosa…”. X-ray diffraction, 2 ligands (N8E, PO4), 16 pockets (best druggability 0.85). MolNFT v1…
- PDB
- 2O5P
- Type
- protein
- Length
- 1,526 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferripyoverdine receptor
- UniProt
- P48632
- Ligands
- N8E, PO4
- Pockets
- 16 · best druggability 0.85
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferripyoverdine receptor | protein | 772 | 8% helix, 55% strand | P48632 |
| B | Ferripyoverdine receptor | protein | 754 | 8% helix, 56% strand | P48632 |
Ligands and binding sites
- N8E · 3,6,9,12,15-pentaoxatricosan-1-ol · ligand · chains A
- PO4 · Phosphate ion · ion · 10 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
16 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 450 | 0.85 | 0.93 | 64 | PO4 |
| 2 | 895 | 0.83 | 0.85 | 129 | PO4 |
| 3 | 709 | 0.76 | 0.82 | 104 | PO4 |
| 4 | 1144 | 0.75 | 0.78 | 85 | empty |
| 5 | 1073 | 0.75 | 0.78 | 89 | empty |
Interfaces
1 interface between chains.
- A–B · 689 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 2O5P · Crystal structure of the full length ferric pyoverdine outer membrane receptor FpvA of… · the same entry in another collection · chain A against A, TM-score 1.00
- P48632 · AlphaFold monomer V2.0 prediction for ferripyoverdine receptor (P48632) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48632
- Elsewhere: RCSB PDB 2O5P · PDBe 2O5P · UniProt P48632
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