MolNFT v1 · #45675 · protein

ULD COMPLEX

2NA1 · Polycomb complex protein bmi-1, polyhomeotic-like 2: “ULD COMPLEX”. Solution nmr, 3 pockets (best druggability 0.49). MolNFT v1 #45675 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2NA1
Type: protein
Length: 145 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polycomb complex protein bmi-1, polyhomeotic-like 2
UniProt: B1ASA2, P35226
Pockets: 3 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 21% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polycomb complex protein bmi-1, polyhomeotic-like 2	protein	145	21% helix, 30% strand	B1ASA2, P35226

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	206	0.49	0.75	17	empty
2	110	0.38	0.74	20	empty
3	65	0.28	0.73	13	empty

Compared structures

2NA1 · ULD complex · the same entry in another collection · chain A against A, TM-score 1.00
P35226 · AlphaFold monomer V2.0 prediction for polycomb complex protein bmi-1 (P35226) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B1ASA2
Every structure of UniProt P35226
Elsewhere: RCSB PDB 2NA1 · PDBe 2NA1 · UniProt B1ASA2 · UniProt P35226

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