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MolNFT v1 · #45434 · protein

Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0

2N2W · Insulin a chain: “Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0”. Solution nmr. MolNFT v1 #45434 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2N2W
Type
protein
Length
51 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Insulin a chain; Insulin B chain
UniProt
P01308

Structure

solution nmr · 2 distinct chains · 41% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AInsulin a chainprotein2152% helix, 0% strandP01308
BInsulin B chainprotein3033% helix, 0% strandP01308

Interfaces

1 interface between chains.

  • A–B · 531 Ų buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide, 2 modified (disulfide, nonstandard).

Compared structures

  • 2N2W · Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0 · the same entry in another collection · chain A against A, TM-score 1.00

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