MolNFT v1 · #44287 · protein

African swine fever virus pol X in the ternary complex with mgdgtp and DNA

2M2V · Repair DNA polymerase X: “African swine fever virus pol X in the ternary complex with mgdgtp and DNA”. Solution nmr, 3 pockets (best druggability 0.74). MolNFT v1 #44287 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2M2V
Type: protein
Length: 174 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Repair DNA polymerase X
EC: 2.7.7.7
UniProt: P42494
Pockets: 3 · best druggability 0.74

Structure

solution nmr · 1 distinct chain · 33% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Repair DNA polymerase X (EC 2.7.7.7)	protein	174	33% helix, 33% strand	P42494

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.74	0.97	19	empty
2	195	0.54	0.78	27	empty
3	60	0.28	0.74	13	empty

Compared structures

2M2V · African Swine Fever Virus Pol X in the ternary complex with MgdGTP and DNA · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42494
Elsewhere: RCSB PDB 2M2V · PDBe 2M2V · UniProt P42494

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