MolNFT v1 · #44279 · protein
Structure of [L-HISB24] insulin analogue at pH 8.0
2M2N · Insulin a chain: “Structure of [L-HISB24] insulin analogue at pH 8.0”. Solution nmr. MolNFT v1 #44279 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2M2N
- Type
- protein
- Length
- 51 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Insulin a chain; Insulin B chain
- UniProt
- P01308
Structure
solution nmr · 2 distinct chains · 51% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Insulin a chain | protein | 21 | 52% helix, 10% strand | P01308 |
| B | Insulin B chain | protein | 30 | 50% helix, 7% strand | P01308 |
Interfaces
1 interface between chains.
- A–B · 711 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 2M2N · Structure of [L-HisB24] insulin analogue at pH 8.0 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01308
- Elsewhere: RCSB PDB 2M2N · PDBe 2M2N · UniProt P01308
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