MolNFT v1 · #44046 · protein

Structure of the GP78CUE domain bound to monubiquitin

2LVO: “Structure of the GP78CUE domain bound to monubiquitin”. Solution nmr. MolNFT v1 #44046 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LVO
Type: protein
Length: 128 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin; E3 ubiquitin-protein ligase amfr
EC: 6.3.2.-
UniProt: P0CG48, Q9UKV5

Structure

solution nmr · 2 distinct chains · 34% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin	protein	76	20% helix, 33% strand	P0CG48
C	E3 ubiquitin-protein ligase amfr (EC 6.3.2.-)	protein	52	56% helix, 0% strand	Q9UKV5

Interfaces

1 interface between chains.

A–C · 742 Å² buried · 18 hydrogen bonds · protein-protein

Compared structures

2LVO · Structure of the gp78CUE domain bound to monubiquitin · the same entry in another collection · chain A against A, TM-score 1.00
Q9UKV5 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase amfr (Q9UKV5) · a predicted model of the same protein · chain C against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0CG48
Every structure of UniProt Q9UKV5
Elsewhere: RCSB PDB 2LVO · PDBe 2LVO · UniProt P0CG48 · UniProt Q9UKV5

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