GL1X · GenesisL1 explorer

MolNFT v1 · #43985 · protein

Yap WW1 in complex with a SMAD7 derived peptide

2LTW · Yorkie homolog: “Yap WW1 in complex with a SMAD7 derived peptide”. Solution nmr. MolNFT v1 #43985 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2LTW
Type
protein
Length
50 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Yorkie homolog; SMAD7 derived peptide
UniProt
P46937, O15105

Structure

solution nmr · 2 distinct chains · 0% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AYorkie homologprotein360% helix, 42% strandP46937
BSMAD7 derived peptideprotein140% helix, 0% strandO15105

Interfaces

1 interface between chains.

  • A–B · 482 Ų buried · 1 hydrogen bond · protein-protein

Compared structures

  • 2LTW · YAP WW1 in complex with a Smad7 derived peptide · the same entry in another collection · chain A against A, TM-score 1.00
  • P46937 · AlphaFold monomer V2.0 prediction for transcriptional coactivator YAP1 (P46937) · a predicted model of the same protein · chain A against A, TM-score 0.59
  • O15105 · AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 7 (O15105) · a predicted model of the same protein · chain B against A, TM-score 0.22

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