MolNFT v1 · #43788 · protein
Identification and structural basis for a novel interaction between VAV2 and ARAP3
2LNW · Guanine nucleotide exchange factor VAV2: “Identification and structural basis for a novel interaction between VAV2 and ARAP3”. Solution nmr. MolNFT v1 #43788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2LNW
- Type
- protein
- Length
- 122 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Guanine nucleotide exchange factor VAV2; Arf-gap with rho-gap domain, ank repeat and pH…
- UniProt
- P52735, Q8WWN8
Structure
solution nmr · 2 distinct chains · 19% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide exchange factor VAV2 | protein | 113 | 20% helix, 26% strand | P52735 |
| B | Arf-gap with rho-gap domain, ank repeat and pH domain- containing protein 3 | protein | 9 | 0% helix, 0% strand | Q8WWN8 |
Interfaces
1 interface between chains.
- A–B · 508 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 2LNW · Identification and structural basis for a novel interaction between Vav2 and Arap3 · the same entry in another collection · chain A against A, TM-score 1.00
- P52735 · AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor VAV2 (P52735) · a predicted model of the same protein · chain A against A, TM-score 0.86
- Q8WWN8 · AlphaFold monomer V2.0 prediction for arf-gap with rho-gap domain, ank repeat and pH… · a predicted model of the same protein · chain B against A, TM-score 0.46
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52735
- Every structure of UniProt Q8WWN8
- Elsewhere: RCSB PDB 2LNW · PDBe 2LNW · UniProt P52735 · UniProt Q8WWN8
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