MolNFT v1 · #43648 · protein
Biphosphorylated (747PY, 759PY) BETA3 integrin cytoplasmic tail under membrane mimetic conditions
2LJE · Integrin beta-3: “Biphosphorylated (747PY, 759PY) BETA3 integrin cytoplasmic tail under membrane mimetic conditions”. Solution nmr, 1 pocket (best druggability 0.34). MolNFT v1 #43648 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2LJE
- Type
- protein
- Length
- 47 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Integrin beta-3
- UniProt
- P05106
- Pockets
- 1 · best druggability 0.34
Structure
solution nmr · 1 distinct chain · 51% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Integrin beta-3 | protein | 47 | 51% helix, 0% strand | P05106 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.34 | 0.79 | 13 | empty |
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 2LJE · Biphosphorylated (747pY, 759pY) beta3 integrin cytoplasmic tail under membrane mimetic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05106
- Elsewhere: RCSB PDB 2LJE · PDBe 2LJE · UniProt P05106
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