MolNFT v1 · #43570 · protein

Solution structure of STT3P

2LGZ · Dolichyl-diphosphooligosaccharide--protein…: “Solution structure of STT3P”. Solution nmr, 6 pockets (best druggability 0.68). MolNFT v1 #43570 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LGZ
Type: protein
Length: 273 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3
EC: 2.4.1.119
UniProt: P39007
Pockets: 6 · best druggability 0.68

Structure

solution nmr · 1 distinct chain · 40% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (EC 2.4.1.119)	protein	273	40% helix, 0% strand	P39007

Pockets

6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	123	0.68	0.90	26	empty
2	92	0.63	0.89	21	empty
3	62	0.62	0.92	17	empty
4	203	0.56	0.79	29	empty
5	275	0.52	0.75	39	empty

Compared structures

2LGZ · Solution structure of STT3P · the same entry in another collection · chain A against A, TM-score 1.00
P39007 · AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein… · a predicted model of the same protein · chain A against A, TM-score 0.37

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39007
Elsewhere: RCSB PDB 2LGZ · PDBe 2LGZ · UniProt P39007

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