MolNFT v1 · #43484 · protein + RNA
Solution structure of human SRSF2 (SC35) rrm in complex with 5'- uccagu-3'
2LEB · SERINE/ARGININE-rich splicing factor 2: “Solution structure of human SRSF2 (SC35) rrm in complex with 5'- uccagu-3'”. Solution nmr. MolNFT v1 #43484 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2LEB
- Type
- protein + RNA
- Length
- 107 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/ARGININE-rich splicing factor 2; RNA (5'-R(*UP*CP*CP*AP*GP*U)-3')
- UniProt
- Q01130
Structure
solution nmr · 2 distinct chains · 20% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/ARGININE-rich splicing factor 2 | protein | 101 | 20% helix, 15% strand | Q01130 |
| B | RNA (5'-R(*UP*CP*CP*AP*GP*U)-3') | rna | 6 | — | — |
Interfaces
1 interface between chains.
- A–B · 1115 Ų buried · 32 hydrogen bonds · protein-nucleic
Compared structures
- 2LEB · Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UCCAGU-3' · the same entry in another collection · chain A against A, TM-score 1.00
- Q01130 · AlphaFold monomer V2.0 prediction for SERINE/ARGININE-rich splicing factor 2 (Q01130) · a predicted model of the same protein · chain A against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01130
- Elsewhere: RCSB PDB 2LEB · PDBe 2LEB · UniProt Q01130
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