UniProt Q01130
Serine/arginine-rich splicing factor 2 (Q01130)
Serine/arginine-rich splicing factor 2 (UniProt Q01130): 8 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q01130
- Protein
- Serine/arginine-rich splicing factor 2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
9 records of Q01130 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KN4 | The structure of the RRM domain of SC35 | solution nmr | A | — | 1 (best 0.43) |
| 2KN4 | The structure of the rrm domain of SC35 | solution nmr | A | — | 1 (best 0.43) |
| 2LEA | Solution structure of human SRSF2 (SC35) RRM | solution nmr | A | — | — |
| 2LEA | Solution structure of human SRSF2 (SC35) rrm | solution nmr | A | — | — |
| 2LEB | Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UCCAGU-3' | solution nmr | A | — | — |
| 2LEB | Solution structure of human SRSF2 (SC35) rrm in complex with 5'- uccagu-3' | solution nmr | A | — | — |
| 2LEC | Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3' | solution nmr | A | — | 1 (best 0.29) |
| 2LEC | Solution structure of human SRSF2 (SC35) rrm in complex with 5'- uggagu-3' | solution nmr | A | — | 1 (best 0.29) |
| Q01130 | AlphaFold monomer V2.0 prediction for SERINE/ARGININE-rich splicing factor 2 (Q01130) | predicted | A | — | — |
Experiment against prediction
- 2LEB chain A against the predicted model Q01130: TM-score 0.76, RMSD 2.70 Å
- 2LEB chain A against the predicted model Q01130: TM-score 0.76, RMSD 2.70 Å
- 2LEC chain A against the predicted model Q01130: TM-score 0.74, RMSD 2.79 Å
- 2LEC chain A against the predicted model Q01130: TM-score 0.74, RMSD 2.79 Å
- 2LEA chain A against the predicted model Q01130: TM-score 0.69, RMSD 1.99 Å
- 2LEA chain A against the predicted model Q01130: TM-score 0.69, RMSD 1.99 Å
- 2KN4 chain A against the predicted model Q01130: TM-score 0.49, RMSD 2.52 Å
- 2KN4 chain A against the predicted model Q01130: TM-score 0.49, RMSD 2.52 Å
- 2KN4 chain A against the predicted model P19909: TM-score 0.39, RMSD 2.43 Å
- 2KN4 chain A against the predicted model P19909: TM-score 0.39, RMSD 2.43 Å
Elsewhere
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