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MolNFT v1 · #43290 · RNA

Chemical probe bound to HIV tar RNA

2L8H: “Chemical probe bound to HIV tar RNA”. Solution nmr, 2 ligands (ARG, L8H), 1 pocket (best druggability 0.53). MolNFT v1 #43290 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2L8H
Type
RNA
Length
29 nucleotides
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
HIV tar RNA
Ligands
ARG, L8H
Pockets
1 · best druggability 0.53

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
AHIV tar RNArna29——

Ligands and binding sites

  • ARG · Arginine · ligand · chains A
  • L8H · 4-methoxynaphthalen-2-amine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11670.530.8022ARG, L8H

Compared structures

  • 2L8H · Chemical probe bound to HIV TAR RNA · the same entry in another collection · chain A against A, TM-score 1.00

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