GL1X · GenesisL1 explorer

MolNFT v1 · #43220 · protein

NMR solution structure of fat domain of fak complexed with LD2 and LD4 motifs of paxillin

2L6F · Focal adhesion kinase 1, LINKER1, paxillin, LINKER2…: “NMR solution structure of fat domain of fak complexed with LD2 and LD4 motifs of paxillin”. Solution nmr, 1 pocket (best druggability 0.37). MolNFT v1 #43220 on GenesisL1: 3D…

PDB
2L6F
Type
protein
Length
176 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Focal adhesion kinase 1, LINKER1, paxillin, LINKER2, paxillin
EC
2.7.10.2
UniProt
Q00944, P49024
Pockets
1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 79% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AFocal adhesion kinase 1, LINKER1, paxillin, LINKER2, paxillin (EC 2.7.10.2)protein17679% helix, 0% strandQ00944, P49024

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1530.370.7913empty

Compared structures

  • 2L6F · NMR Solution structure of FAT domain of FAK complexed with LD2 and LD4 motifs of PAXILLIN · the same entry in another collection · chain A against A, TM-score 1.00
  • Q00944 · AlphaFold monomer V2.0 prediction for focal adhesion kinase 1 (Q00944) · a predicted model of the same protein · chain A against A, TM-score 0.63
  • P49024 · AlphaFold monomer V2.0 prediction for paxillin (P49024) · a predicted model of the same protein · chain A against A, TM-score 0.24

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.