MolNFT v1 · #43153 · protein

The solution structure of calcium bound CIB1

2L4H · Calcium and integrin-binding protein 1: “The solution structure of calcium bound CIB1”. Solution nmr, 1 ligand (CA), 2 pockets (best druggability 0.48). MolNFT v1 #43153 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2L4H
Type: protein
Length: 184 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calcium and integrin-binding protein 1
UniProt: Q99828
Ligands: CA
Pockets: 2 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 58% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calcium and integrin-binding protein 1	protein	184	58% helix, 3% strand	Q99828

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.48	0.80	27	empty
2	80	0.39	0.77	14	empty

Compared structures

2L4H · The Solution Structure of Calcium Bound CIB1 · the same entry in another collection · chain A against A, TM-score 1.00
Q99828 · AlphaFold monomer V2.0 prediction for calcium and integrin-binding protein 1 (Q99828) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99828
Elsewhere: RCSB PDB 2L4H · PDBe 2L4H · UniProt Q99828

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