MolNFT v1 · #43106 · protein

Structure of the DAP12 transmembrane homodimer

2L34 · Tyro protein tyrosine kinase-binding protein: “Structure of the DAP12 transmembrane homodimer”. Solution nmr. MolNFT v1 #43106 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2L34
Type: protein
Length: 66 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tyro protein tyrosine kinase-binding protein
UniProt: O43914

Structure

solution nmr · 1 distinct chain · 73% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Tyro protein tyrosine kinase-binding protein	protein	33	73% helix, 0% strand	O43914

Interfaces

1 interface between chains.

A–B · 692 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2L34 · Structure of the DAP12 transmembrane homodimer · the same entry in another collection · chain B against B, TM-score 1.00
O43914 · AlphaFold monomer V2.0 prediction for tyro protein tyrosine kinase- binding protein… · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43914
Elsewhere: RCSB PDB 2L34 · PDBe 2L34 · UniProt O43914

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