MolNFT v1 · #43087 · protein

Solution structure of the coiled-coil complex between MBD2 and P66ALPHA

2L2L · Transcriptional repressor P66-alpha: “Solution structure of the coiled-coil complex between MBD2 and P66ALPHA”. Solution nmr. MolNFT v1 #43087 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2L2L
Type: protein
Length: 79 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional repressor P66-alpha; Methyl-cpg-binding domain protein 2
UniProt: Q86YP4, Q9UBB5

Structure

solution nmr · 2 distinct chains · 68% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional repressor P66-alpha	protein	43	72% helix, 0% strand	Q86YP4
B	Methyl-cpg-binding domain protein 2	protein	36	64% helix, 0% strand	Q9UBB5

Interfaces

1 interface between chains.

A–B · 705 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

2L2L · Solution structure of the coiled-coil complex between MBD2 and p66alpha · the same entry in another collection · chain A against A, TM-score 1.00
Q86YP4 · AlphaFold monomer V2.0 prediction for transcriptional repressor P66-alpha (Q86YP4) · a predicted model of the same protein · chain A against A, TM-score 0.72
Q9UBB5 · AlphaFold monomer V2.0 prediction for methyl-cpg-binding domain protein 2 (Q9UBB5) · a predicted model of the same protein · chain B against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86YP4
Every structure of UniProt Q9UBB5
Elsewhere: RCSB PDB 2L2L · PDBe 2L2L · UniProt Q86YP4 · UniProt Q9UBB5

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