MolNFT v1 · #42968 · protein

Calmodulin, C-terminal domain, F92E mutant

2KZ2: “Calmodulin, C-terminal domain, F92E mutant”. Solution nmr, 1 ligand (CA), 1 pocket (best druggability 0.67). MolNFT v1 #42968 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KZ2
Type: protein
Length: 93 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calmodulin
UniProt: P62149
Ligands: CA
Pockets: 1 · best druggability 0.67

Structure

solution nmr · 1 distinct chain · 53% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calmodulin	protein	93	53% helix, 2% strand	P62149

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	380	0.67	0.80	37	empty

Compared structures

2KZ2 · Calmodulin, C-terminal domain, F92E mutant · the same entry in another collection · chain A against A, TM-score 1.00
P62149 · AlphaFold monomer V2.0 prediction for calmodulin (P62149) · a predicted model of the same protein · chain A against A, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62149
Elsewhere: RCSB PDB 2KZ2 · PDBe 2KZ2 · UniProt P62149

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.