MolNFT v1 · #42854 · protein
Solution structure of the CBX7 chromodomain in complex with a H3K27ME2 peptide
2KVM · Chromobox protein homolog 7: “Solution structure of the CBX7 chromodomain in complex with a H3K27ME2 peptide”. Solution nmr. MolNFT v1 #42854 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KVM
- Type
- protein
- Length
- 87 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromobox protein homolog 7; Histone H3 peptide (residues 15-30) with dimethylated lysine…
- UniProt
- Q8VDS3
Structure
solution nmr · 2 distinct chains · 21% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chromobox protein homolog 7 | protein | 71 | 25% helix, 31% strand | Q8VDS3 |
| B | Histone H3 peptide (residues 15-30) with dimethylated lysine 27 | protein | 16 | 0% helix, 0% strand | — |
Interfaces
1 interface between chains.
- A–B · 808 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (methylation).
Compared structures
- 2KVM · Solution structure of the CBX7 chromodomain in complex with a H3K27me2 peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q8VDS3 · AlphaFold monomer V2.0 prediction for chromobox protein homolog 7 (Q8VDS3) · a predicted model of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8VDS3
- Elsewhere: RCSB PDB 2KVM · PDBe 2KVM · UniProt Q8VDS3
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