MolNFT v1 · #42769 · protein
Solution structure of human stem cell transcription factor nanog homeodomain fragment
2KT0 · Homeobox protein nanog: “Solution structure of human stem cell transcription factor nanog homeodomain fragment”. Solution nmr, 2 pockets (best druggability 0.47). MolNFT v1 #42769 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2KT0
- Type
- protein
- Length
- 84 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Homeobox protein nanog
- UniProt
- Q6NSW7
- Pockets
- 2 · best druggability 0.47
Structure
solution nmr · 1 distinct chain · 43% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Homeobox protein nanog | protein | 84 | 43% helix, 0% strand | Q6NSW7 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 69 | 0.47 | 0.83 | 17 | empty |
| 2 | 95 | 0.37 | 0.74 | 15 | empty |
Compared structures
- 2KT0 · Solution structure of human stem cell transcription factor Nanog homeodomain fragment · the same entry in another collection · chain A against A, TM-score 1.00
- Q6NSW7 · AlphaFold monomer V2.0 prediction for homeobox protein NANOGP8 (Q6NSW7) · a predicted model of the same protein · chain A against A, TM-score 0.49
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NSW7
- Elsewhere: RCSB PDB 2KT0 · PDBe 2KT0 · UniProt Q6NSW7
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