MolNFT v1 · #42762 · protein
NMR structures of tm domain of the N-acetylcholine receptor B2 subunit
2KSR · Neuronal acetylcholine receptor subunit beta-2: “NMR structures of tm domain of the N-acetylcholine receptor B2 subunit”. Solution nmr, 3 pockets (best druggability 0.72). MolNFT v1 #42762 on GenesisL1: 3D structure, binding sites…
- PDB
- 2KSR
- Type
- protein
- Length
- 140 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neuronal acetylcholine receptor subunit beta-2
- UniProt
- P17787
- Pockets
- 3 · best druggability 0.72
Structure
solution nmr · 1 distinct chain · 68% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuronal acetylcholine receptor subunit beta-2 | protein | 140 | 68% helix, 0% strand | P17787 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 305 | 0.72 | 0.84 | 44 | empty |
| 2 | 228 | 0.62 | 0.81 | 29 | empty |
| 3 | 51 | 0.31 | 0.77 | 13 | empty |
Compared structures
- 2KSR · NMR structures of TM domain of the n-Acetylcholine receptor b2 subunit · the same entry in another collection · chain A against A, TM-score 1.00
- P17787 · AlphaFold monomer V2.0 prediction for neuronal acetylcholine receptor subunit beta-2… · a predicted model of the same protein · chain A against A, TM-score 0.65
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17787
- Elsewhere: RCSB PDB 2KSR · PDBe 2KSR · UniProt P17787
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