MolNFT v1 · #42759 · protein
EPHA2:SHIP2 SAM:SAM complex
2KSO · Ephrin type-a receptor 2: “EPHA2:SHIP2 SAM:SAM complex”. Solution nmr. MolNFT v1 #42759 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KSO
- Type
- protein
- Length
- 124 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ephrin type-a receptor 2; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
- UniProt
- P29317, O15357
Structure
solution nmr · 2 distinct chains · 58% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ephrin type-a receptor 2 | protein | 65 | 63% helix, 0% strand | P29317 |
| B | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | protein | 59 | 53% helix, 0% strand | O15357 |
Interfaces
1 interface between chains.
- A–B · 521 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 2KSO · EphA2:SHIP2 SAM:SAM complex · the same entry in another collection · chain A against A, TM-score 1.00
- P29317 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 2 (P29317) · a predicted model of the same protein · chain A against A, TM-score 0.93
- O15357 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate… · a predicted model of the same protein · chain B against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29317
- Every structure of UniProt O15357
- Elsewhere: RCSB PDB 2KSO · PDBe 2KSO · UniProt P29317 · UniProt O15357
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